Entropy Maxima was founded by Noel Carrascal in 2018. The goal of the company is to accelerate the pace of discovery of new protein-based therapeutics and materials.

The San Francisco based company's approach to its goal is to develop new interpretations of established thermodynamic principles that lead to new discoveries.

Looking at computational chemistry problems from the entropy maxima perspective, as opposed to the equivalent energy minima approach, opens new avenues of discovery. Reviewing the literature with this 'inverse' mindset reveals opportunities hidden from other researchers.

In simulations, for example, being stuck in an energy minima could prevent us from proper ensemble sampling while an entropy maxima discovery (a phase transition signaled by a pressure increase) indicates something very special.

Studies on solvent models from this opposite mindset have already given interesting insights that have lead to better fine tuning of simulations, free energy and convergence calculation methods.

Entropy Maxima is doing a full reverse path integration of the field's vast literature in search for more innovative insights to apply to today's challenges in bio-tech.

Noel Carrascal received a PhD in Applied Mathematics and Statistics to Computational Biology from Stony Brook University in 2011. He followed that with a postdoctoral research fellowship in Genetics at Albert Einstein school of Medicine. He transition to the private sector to work in finance at Prudential in New York before moving to the San Francisco bay area in 2015.

From the moment he arrived to the west coast, his focus has been on starting a company with an innovative approach to computational protein design. Noel enhanced his skill set to achieve this goal by working in different fields such as data science, intellectual property, bioinformatics, cancer diagnosis and protein design research. He used all of his accumulated experience, ideas and skills to establish Entropy Maxima, LLC, in 2018.

Noel's combination of skills and well rounded background suits his entrepreneur personality. He also holds a bachelors of arts in chemistry from Stony Brook university, and a bachelors of science in computer engineering from Florida International University.